Head to head
Ipamorelin vs Sermorelin
Two compounds, one grading system.
On human evidence, Sermorelin currently leads: well researched versus emerging.
01
At a glance
IpamorelinEmerging
Selective growth-hormone secretagogue. Raises GH; downstream benefits less proven.
118publications
2RCTs
SermorelinWell researched
GHRH fragment with a long clinical history, once used diagnostically.
484publications
23RCTs
02
Side by side
| Attribute | Ipamorelin | Sermorelin |
|---|---|---|
| Goal | Muscle & performance | Hormonal support |
| Evidence | Emerging | Well researched |
| Publications | 118 | 484 |
| Randomised trials | 2 | 23 |
| Sport (WADA) | S2 — prohibited | S2 — prohibited |
| US compounding | — | — |
03
Claims vs data
Ipamorelin — claims vs data
| Increases growth hormone release | supported |
| Produces meaningful muscle gain alone | weak evidence |
Sermorelin — claims vs data
| Stimulates natural growth-hormone release | supported |
| Reverses age-related decline | overreach |