Head to head
Melanotan I vs PT-141
Two compounds, one grading system.
On human evidence, PT-141 currently leads: fda approved versus well researched.
01
At a glance
Melanotan IWell researched
Melanocortin agonist; the regulated version (afamelanotide) is approved for a rare condition.
66publications
2RCTs
02
Side by side
| Attribute | Melanotan I | PT-141 |
|---|---|---|
| Goal | Skin & cosmetic | Sexual health |
| Evidence | Well researched | FDA approved |
| Publications | 66 | 112 |
| Randomised trials | 2 | 6 |
| Sport (WADA) | — | not listed |
| US compounding | — | — |
03
Claims vs data
Melanotan I — claims vs data
| Approved as afamelanotide for erythropoietic protoporphyria | supported |
| Increases tanning with less UV exposure | partially true |
| Safe for unsupervised cosmetic use | overreach |
PT-141 — claims vs data
| Approved for low sexual desire in premenopausal women | supported |
| Nausea is a common side effect | supported |
| Works like PDE5 drugs such as sildenafil | overreach |