HCG
1104 RCTsFDA approved
| Supports testicular function during TRT | supported |
| Causes weight loss (HCG diet) | overreach |
Goal matrix
Hormonal support
Every compound we track for this goal.
2 FDA approved5 Well researched
01
The matrix
HMG
210 RCTsFDA approved
| Established fertility medicine under specialist care | supported |
| Useful as a general wellness compound | overreach |
Gonadorelin
57 RCTsWell researched
| Triggers a measurable rise in LH and FSH within minutes of administration | supported |
| Pulsatile pump-delivered administration can induce ovulation in primary hypothalamic amenorrhoea | supported |
| Pulsatile regimens raise testosterone in men with hypogonadotropic hypogonadism | partially true |
| Maintains testicular size and fertility in men using testosterone therapy | overreach |
GHRP-2
50 RCTsWell researched
| Raises circulating growth hormone in humans | supported |
| Holds a national regulatory approval as a diagnostic agent | supported |
| Increases appetite and food intake | partially true |
| Builds muscle and reduces fat in healthy adults | overreach |
Hexarelin
29 RCTsWell researched
| Raises circulating growth hormone in humans | supported |
| Acutely increases left-ventricular ejection fraction after a single intravenous administration | partially true |
| Protects heart muscle from ischaemic injury through CD36 | animal data only |
| Is a treatment for heart failure or heart disease | overreach |
Sermorelin
23 RCTsWell researched
| Stimulates natural growth-hormone release | supported |
| Reverses age-related decline | overreach |
TRH
15 RCTsWell researched
| A single intravenous administration produces a measurable rise in thyroid-stimulating hormone | supported |
| It raises circulating prolactin as well as TSH | supported |
| Produces transient mood elevation in small controlled studies in depression | weak evidence |
| Restores thyroid function, metabolic rate or energy in people with a normal thyroid axis | overreach |
02