L-Carnitine
742 RCTsExtensively studied
| Corrects clinical carnitine deficiency | supported |
| Modest, context-dependent performance effects | partially true |
| Burns fat in healthy adults | weak evidence |
Goal matrix
Muscle & performance
Every compound we track for this goal.
1 Extensively studied1 Well researched1 Emerging3 Limited evidence
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The matrix
GHRP-6
23 RCTsWell researched
| Releases growth hormone in humans | supported |
| Also raises ACTH, cortisol and prolactin | supported |
| Stimulates appetite | partially true |
| Accelerates injury healing and joint repair | overreach |
Ipamorelin
2 RCTsEmerging
| Increases growth hormone release | supported |
| Produces meaningful muscle gain alone | weak evidence |
IGF-1 LR3
1 RCTsLimited evidence
| Increases muscle protein synthesis | partially true |
| Safe for long-term use | overreach |
Follistatin 344
0 RCTsLimited evidence
| Dramatic muscle growth in humans | overreach |
| Inhibits myostatin | preclinical only |
PEG-MGF
0 RCTsLimited evidence
| Mechanical loading increases endogenous MGF expression in human muscle | supported |
| Administered PEG-MGF activates satellite cells and drives muscle repair | preclinical only |
| PEGylation keeps its action local to the injection site | weak evidence |
| Has been tested in randomised human trials | overreach |
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