Selank
2 RCTsEmerging
| Anxiolytic effect reported in Russian clinical studies | partially true |
| A non-sedating replacement for prescribed treatment | weak evidence |
Goal matrix
Cognition & mood
Every compound we track for this goal.
2 Emerging3 Limited evidence
01
The matrix
Semax
2 RCTsEmerging
| Used clinically in Russia for stroke and cognitive indications | supported |
| Raises BDNF and neuroplasticity | preclinical only |
| Enhances cognition in healthy adults | weak evidence |
PE-22-28
1 RCTsLimited evidence
| Antidepressant-like effects in rodents | animal data only |
| A validated treatment for depression | overreach |
Dihexa
0 RCTsLimited evidence
| Increases dendritic spine formation in cultured hippocampal neurons | preclinical only |
| Improves maze performance in scopolamine-treated and aged rodents | animal data only |
| Works by potentiating hepatocyte growth factor at c-Met | weak evidence |
| Seven orders of magnitude more potent than BDNF, and so improves cognition in humans | overreach |
P21
0 RCTsLimited evidence
| Promotes neurogenesis in animal models | animal data only |
| Improves human memory and learning | overreach |
02